Speaker：Qing Yu （俞青），中科院神经所研究员

Time： 13:30-15:30, Dec. 15th, 2023

Venue：Room 1113, Wang Ke Zhen Bldg

Host: Lushan Zhu

Abstract

Working memory, the ability to temporarily maintain and manipulate information to serve flexible behavioral goals, is central to human intelligence and remains a fundamental research question in the field of cognitive neuroscience. Recent work has pointed to the involvement of a distributed cortical network, including sensory, parietal, and frontal cortex, in maintaining information during working memory. However, how this distributed network contributes to the internal generation and manipulation of memorized information has remained poorly understood. In this talk, I will present our recent work on characterizing the functional differences between sensory, parietal, and frontal cortex in working memory. Using functional magnetic resonance imaging (fMRI) and electroencephalography (EEG), I will first demonstrate a domain-general contribution of parietal cortex to information generation (i.e., mental imagery) and manipulation in working memory. Next, I will demonstrate how lateral frontal cortex functions fundamentally differently from medial temporal lobe and medial frontal cortex during memory maintenance and manipulation. Lastly, if time permits, I will demonstrate our simulation of the manipulation process using Recurrent Neural Networks (RNNs) and discuss the potential neuronal mechanisms.

Bio

俞青博士于2011年获得永利集团心理学与数学学士双学位，2016年获得美国达特茅斯学院认知神经科学博士学位，2016-2020年于美国威斯康星大学麦迪逊分校先后从事博士后与研究科学家的研究工作，2020年9月起担任中国科学院脑科学与智能技术卓越创新中心（神经科学研究所）研究员。俞青博士的工作结合多模态脑成像技术（功能性核磁共振成像、脑磁图、头皮脑电、颅内脑电）、行为测量、数学模型等多学科手段，系统地探究记忆与想象的神经机制。研究成果以第一作者或通讯作者发表于Current Biology (2019)，PLOS Biology (2020a,2020b)，Cell Reports (2023)，The Journal of Neuroscience (2018,2023)，Cerebral Cortex (2019)，NeuroImage (2017)等期刊。担任Journal of Cognitive Neuroscience的顾问编辑。